Episode Breakdown:
00:00 – Intro
00:21 – Why materials matter in medical device design
01:14 – Dr. Upma Sharma’s path from engineer to medtech CEO
03:01 – Arsenal’s founding story with Bob Langer and George Whitesides
06:20 – DARPA’s battlefield challenge and the birth of Rescue Foam
10:15 – How “Fix-a-Flat” foam saves lives internally
11:44 – Neocast: A liquid embolic inspired by toothpaste physics
14:33 – How Arsenal removes the “art” from embolic injections
16:14 – Arsenal’s pipeline across trauma, neuro, and women’s health
19:26 – Why chronic brain bleeds may surpass stroke
22:38 – How Arsenal approaches spinouts and strategic exits
23:42 – Fundraising goals and IDE milestones
25:49 – Clinicians’ role in shaping product development
28:14 – The broader potential of Arsenal’s biomaterials platform
29:48 – First-in-human data coming to SNIS and LSI London
30:12 – Outro
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