Lung cancer remains the most lethal cancer worldwide, and traditional biopsy approaches still leave critical gaps. In this episode, interventional pulmonologist Dr. Steven Kovacs shares how real-time metabolic imaging inside the bronchoscopy suite is transforming how clinicians assess biopsy adequacy.
Episode Breakdown
00:00 – Opening remarks: the challenge of lung cancer diagnosis
01:17 – Introducing Dr. Steven Kovacs
02:11 – Journey through bronchoscopy: from navigation to robotics
05:11 – The problem with current biopsy yields and ROSE
07:29 – Why imaging tool-in-lesion is not enough
09:59 – Metabolic activity as a new “PET scan for cells”
12:16 – How dynamic cell imaging works in real time
14:45 – Preserving tissue for pathology and sequencing
17:15 – Differentiating inflammation, necrosis, and malignancy in the same lesion
19:37 – Case studies: when pathology said “negative,” but malignancy was present
22:01 – Adequacy as a clinical responsibility, not just pathology’s burden
24:07 – The future of bronchoscopy workflows and precision medicine
27:32 – Audience Q&A: diagnostic adequacy and workflow efficiency
30:52 – Audience Q&A: reducing procedure time and anesthesia costs
34:41 – Audience Q&A: handling tissue and specimen prep
38:18 – Audience Q&A: impact on indeterminate biopsies
43:12 – Audience Q&A: adequacy for NGS and downstream testing
47:20 – Hospital administration and value analysis: time savings and cost impact
50:05 – Surgical use cases and margin evaluation
52:25 – Adoption and workflow integration: overcoming learning curves
53:32 – Closing thanks and replay reminder
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